NAB2 anticorps (Cy3)

N° du produit ABIN1408335

Cet anticorps anti-NAB2 est un anticorps Lapin Polyclonal détectant NAB2 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NAB2 anticorps (Cy3) (ABIN1408335)

Antigène: NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAB2 est conjugé à/à la Cy3

Application: Western Blotting (WB)

Détail du produit anti-NAB2 anticorps (Cy3)

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NAB2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NAB2

Antigène: NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))

Autre désignation: Nab2/Mader

Sujet:

Synonyms: EGR 1 binding protein 2, EGR-1-binding protein 2, EGR1 binding protein 2, MADER, Melanoma associated delayed early response protein, Melanoma-associated delayed early response protein, MGC75085, Nab 2, nab2, NAB2_HUMAN, NGFI A binding protein 2 EGR1 binding protein 2, NGFI A binding protein 2, NGFI-A-binding protein 2, Protein MADER.

Background: Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2 are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 localizes to chromosome 12q13.3-14.1, a region that is rearranged in several solid tumors, lipomas, and liposarcomas.