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ATXN7 anticorps (AA 301-400) (Cy3)

ATXN7 Reactivité: Souris, Rat WB, IF (p), IF (cc) Hôte: Lapin Polyclonal Cy3
N° du produit ABIN1408449
  • Antigène Voir toutes ATXN7 Anticorps
    ATXN7 (Ataxin 7 (ATXN7))
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivité
    • 34
    • 26
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Souris, Rat
    Hôte
    • 47
    • 1
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATXN7 est conjugé à/à la Cy3
    Application
    • 37
    • 23
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Ataxin 7
    Isotype
    IgG
    Top Product
    Discover our top product ATXN7 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ATXN7 (Ataxin 7 (ATXN7))
    Autre désignation
    Ataxin 7 (ATXN7 Produits)
    Synonymes
    anticorps MGC82940, anticorps ADCAII, anticorps OPCA3, anticorps SCA7, anticorps A430107N12Rik, anticorps AI627028, anticorps Sca7, anticorps ataxin-7, anticorps RGD1562692, anticorps ataxin 7 L homeolog, anticorps ataxin 7, anticorps atxn7.L, anticorps atxn7, anticorps ATXN7, anticorps Atxn7
    Sujet

    Synonyms: Ataxin7, Ataxin-7, ADCAII, ATXN 7, OPCA III, OPCA3, SCA 7, SCA7, Spinocerebellar Ataxia 7, Spinocerebellar ataxia type 7 protein, ATX7_HUMAN.

    Background: The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).

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