NOVA1 anticorps (AA 411-510) (HRP)

N° du produit ABIN1408490

L’anticorps Lapin Polyclonal anti-NOVA1 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter NOVA1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NOVA1 anticorps (AA 411-510) (HRP) (ABIN1408490)

Antigène: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOVA1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-NOVA1 anticorps (HRP)

Épitope: AA 411-510

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NOVA1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NOVA1

Antigène: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Autre désignation: Nova1

Sujet:

Synonyms: Neuro oncological ventral antigen 1, Neuro-oncological ventral antigen 1, NOVA 1, Nova-1, Nova1, NOVA1_HUMAN, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, RNA binding protein Nova 1, RNA-binding protein Nova-1, Ventral neuron specic protein 1, Ventral neuron-specic protein 1.

Background: Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).

UniProt: P51513