RIMS3 anticorps (AA 21-120) (HRP)

N° du produit ABIN1408700

L’anticorps Lapin Polyclonal anti-RIMS3 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter RIMS3 dans des échantillons de Humain.

Aperçu rapide pour RIMS3 anticorps (AA 21-120) (HRP) (ABIN1408700)

Antigène: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIMS3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-RIMS3 anticorps (HRP)

Épitope: AA 21-120

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RIMS3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RIMS3

Antigène: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Autre désignation: RIMS3

Sujet:

Synonyms: NIM 3, NIM3, Rab 3 interacting molecule 3, Regulating synaptic membrane exocytosis 3, Regulating synaptic membrane exocytosis protein 3, RIMS 3, RIMS-3, RIM 3, RIM3, RIM3 gamma, RIMS3, RIMS3_HUMAN.

Background: Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis and functions in an inhibitory capacity, controlling the recruitment and pooling of secretory vesicles at the plasma membrane. The Rim (Rab 3 interacting molecule) family of proteins (Rim1, Rim2, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release. Rim3, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, is a 308 amino acid member of the Rim family. Localized to the synapse and to cell junctions, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis. Rim3, a protein that may be phosphorylated upon DNA damage, is expressed throughout the body with highest levels present in brain tissue.

ID gène: 9783

Pathways: Stem Cell Maintenance, Synaptic Vesicle Exocytosis