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Synaptojanin 2 anticorps (AA 401-500) (Cy5)

SYNJ2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1408804
  • Antigène Voir toutes Synaptojanin 2 (SYNJ2) Anticorps
    Synaptojanin 2 (SYNJ2)
    Épitope
    • 14
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    Reactivité
    • 41
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 37
    • 4
    Lapin
    Clonalité
    • 38
    • 3
    Polyclonal
    Conjugué
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Synaptojanin 2 est conjugé à/à la Cy5
    Application
    • 34
    • 14
    • 12
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Synaptojanin 2
    Isotype
    IgG
    Top Product
    Discover our top product SYNJ2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Synaptojanin 2 (SYNJ2)
    Autre désignation
    Synaptojanin 2 (SYNJ2 Produits)
    Synonymes
    anticorps SYNJ2, anticorps INPP5H, anticorps AI481647, anticorps SJ2, anticorps mKIAA0348, anticorps synaptojanin 2, anticorps synaptojanin-2, anticorps SYNJ2, anticorps LOC100074269, anticorps synj2, anticorps Synj2
    Sujet

    Synonyms: 5-trisphosphate 5-phosphatase 2, Inositol phosphate 5' phosphatase 2, INPP 5H, INPP5H, KIAA0348, MGC44422, SJ2, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2, Synaptic inositol-1, Synaptojanin-2, Synaptojanin2, SYNJ 2, Synj2, SYNJ2_HUMAN.

    Background: The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.

    ID gène
    8871
    Pathways
    Inositol Metabolic Process
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