MC4R anticorps (AA 1-50) (Cy3)

N° du produit ABIN1409043

Cet anticorps anti-MC4R est un anticorps Lapin Polyclonal détectant MC4R dans IF (cc) et IF (p). Adapté pour Humain, Rat et Souris.

Aperçu rapide pour MC4R anticorps (AA 1-50) (Cy3) (ABIN1409043)

Antigène: MC4R (Melanocortin 4 Receptor (MC4R))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MC4R est conjugé à/à la Cy3

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MC4R anticorps (Cy3)

Épitope: AA 1-50

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MC4 Receptor

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MC4R

Antigène: MC4R (Melanocortin 4 Receptor (MC4R))

Autre désignation: MC4 Receptor

Sujet:

Synonyms: MC4 R, MC4-R, MC4R, MC4R_HUMAN, Melanocortin 4 receptor, Melanocortin receptor 4, MGC126851, MGC138197.

Background: The melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.

ID gène: 4160

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour