MC4R anticorps (AA 1-50) (HRP)

N° du produit ABIN1409048

L’anticorps Lapin Polyclonal anti-MC4R a été validé pour ELISA et IHC (fro). Il convient pour détecter MC4R dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MC4R anticorps (AA 1-50) (HRP) (ABIN1409048)

Antigène: MC4R (Melanocortin 4 Receptor (MC4R))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MC4R est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MC4R anticorps (HRP)

Épitope: AA 1-50

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MC4 Receptor

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MC4R

Antigène: MC4R (Melanocortin 4 Receptor (MC4R))

Autre désignation: MC4 Receptor

Sujet:

Synonyms: MC4 R, MC4-R, MC4R, MC4R_HUMAN, Melanocortin 4 receptor, Melanocortin receptor 4, MGC126851, MGC138197.

Background: The melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.

ID gène: 4160

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour