TNRC6B anticorps (AA 25-70) (HRP)

N° du produit ABIN1409462

L’anticorps Lapin Polyclonal anti-TNRC6B a été validé pour WB, ELISA, IHC (fro) et IHC (p). Il convient pour détecter TNRC6B dans des échantillons de Humain.

Aperçu rapide pour TNRC6B anticorps (AA 25-70) (HRP) (ABIN1409462)

Antigène: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNRC6B est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TNRC6B anticorps (HRP)

Épitope: AA 25-70

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TNRC6B

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TNRC6B

Antigène: TNRC6B (Trinucleotide Repeat Containing 6B (TNRC6B))

Autre désignation: TNRC6B

Sujet:

Synonyms: KIAA1093, TNRC 6B, Trinucleotide repeat containing 6B, Trinucleotide repeat containing gene 6B protein, TNR6B_HUMAN.

Background: TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway