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PKD1L3 anticorps (AA 121-220) (Cy7)

PKD1L3 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1410258
  • Antigène Voir toutes PKD1L3 Anticorps
    PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
    Épitope
    • 14
    • 5
    AA 121-220
    Reactivité
    Humain
    Hôte
    • 19
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PKD1L3 est conjugé à/à la Cy7
    Application
    • 12
    • 12
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PKD1L3
    Isotype
    IgG
    Top Product
    Discover our top product PKD1L3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
    Autre désignation
    PKD1L3 (PKD1L3 Produits)
    Synonymes
    anticorps polycystic kidney disease 1 like 3, anticorps polycystin 1 like 3, transient receptor potential channel interacting, anticorps Pkd1l3, anticorps PKD1L3
    Sujet

    Synonyms: PC1 like 3 protein, Polycystic kidney disease 1 like 3, Polycystic kidney disease protein 1 like 3, Polycystin 1 like 3, Polycystin 1L3,PK1L3_HUMAN.

    Background: Polycystin-1L3 is a 1,732 amino acid multi-pass membrane protein that contains one PLAT domain, one GPS domain and one C-type lectin domain. Expressed at high levels in placenta and present at lower levels in lung and heart, Polycystin-1L3 is thought to function as an ion-channel regulator that may interact with Polycystin-L and play a role in heteromeric taste channels. The gene encoding Polycystin-1L3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

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