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Calsyntenin 1 anticorps (AA 501-600) (Cy7)

CLSTN1 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1410384
  • Antigène Voir toutes Calsyntenin 1 (CLSTN1) Anticorps
    Calsyntenin 1 (CLSTN1)
    Épitope
    • 14
    • 14
    • 9
    • 2
    • 1
    • 1
    • 1
    AA 501-600
    Reactivité
    • 38
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 38
    Lapin
    Clonalité
    • 37
    • 1
    Polyclonal
    Conjugué
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Calsyntenin 1 est conjugé à/à la Cy7
    Application
    • 38
    • 19
    • 12
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Calsyntenin 1
    Isotype
    IgG
    Top Product
    Discover our top product CLSTN1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Calsyntenin 1 (CLSTN1)
    Autre désignation
    CLSTN1/Calsyntenin 1 (CLSTN1 Produits)
    Synonymes
    anticorps CALSYNTENIN-1, anticorps fm67g03, anticorps wu:fk52g02, anticorps wu:fm67g03, anticorps zgc:153744, anticorps zgc:56528, anticorps clstn1, anticorps 1810034E21Rik, anticorps Cst-1, anticorps Cstn1, anticorps ALC-ALPHA, anticorps CDHR12, anticorps CSTN1, anticorps PIK3CD, anticorps XB31alpha, anticorps alcalpha1, anticorps alcalpha2, anticorps calsyntenin 1, anticorps calsyntenin 3, anticorps beta-catenin-interacting protein 1, anticorps calsyntenin-1, anticorps CLSTN1, anticorps clstn1, anticorps clstn3, anticorps LOC100356725, anticorps LOC100435584, anticorps Clstn1, anticorps LOC479600
    Sujet

    Synonyms: Alc alpha, Alc-alpha, Alcadein alpha 1, Alcadein alpha, Alcadein-alpha, alcalpha1, alcalpha2, Alzheimer related cadherin like protein, Alzheimer-related cadherin-like protein, Calsyntenin-1, Calsyntenin1, CLSTN 1, Clstn1, CS1, CSTN1, CSTN1_HUMAN, CTF1-alpha, FLJ32258, KIAA0911, Non classical cadherin XB31alpha, Non-classical cadherin XB31alpha, PIK3CD, SAlc-alpha, XB31alpha.

    Background: Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-1, also known as CSTN1, PIK3CD, Alzheimer-related cadherin-like protein, non-classical cadherin XB31alpha, KIAA0911, ALC-ALPHA, alcalpha1, alcalpha2 or FLJ32258, is a 981 amino acid single-pass type I membrane protein that localizes to the membrane of endoplasmic reticulum, Golgi apparatus, cell projections and postsynaptic cells. Expressed in brain, calsyntenin-1 is also found at lower levels in placenta, skeletal muscle, heart and kidney. Calsyntenin-1 binds synaptic Ca2+ with its cytoplasmic domain and plays a role in extracellular proteolysis. Calsyntenin-1 is also known to form a complex with X11 Beta and APP to suppress the metabolic cleavage of APP, and docks vesicular cargo to KLC1. Calsyntenin-1 may be related to the development or progression of Alzheimer?s disease, and two calsyntenin-1 isoforms are produced as a result of alternative splicing events.

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