PICALM anticorps (AA 251-350) (Cy5)

N° du produit ABIN1410502

Cet anticorps Lapin Polyclonal détecte spécifiquement PICALM dans WB, IF (cc) et IF (p). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour PICALM anticorps (AA 251-350) (Cy5) (ABIN1410502)

Antigène: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PICALM est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PICALM anticorps (Cy5)

Épitope: AA 251-350

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Horse,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PICALM/CALM

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PICALM

Antigène: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Autre désignation: PICALM/CALM

Sujet:

Synonyms: Clathrin assembly lymphoid myeloid leukemia, Clathrin assembly lymphoid myeloid leukemia protein, CLTH, LAP, Phosphatidylinositol-binding clathrin assembly protein, PICAL_HUMAN, PICALM.

Background: Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of clathrin binding adaptin proteins and two smaller subunits known as AP50 and AP17. The Alpha- and Beta-Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. Alpha-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP180 (also designated AP-3 or F1-20) is a synapse-specific clathrin assembly protein. The protein CALM (clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in clathrin assembly.

Pathways: Synaptic Membrane