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Receptor Accessory Protein 1 anticorps (AA 53-150) (Cy7)

REEP1 Reactivité: Souris WB, IF (p), IF (cc) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1411008
  • Antigène Voir toutes Receptor Accessory Protein 1 (REEP1) Anticorps
    Receptor Accessory Protein 1 (REEP1)
    Épitope
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 53-150
    Reactivité
    • 24
    • 11
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 25
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Receptor Accessory Protein 1 est conjugé à/à la Cy7
    Application
    • 24
    • 12
    • 12
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human REEP1
    Isotype
    IgG
    Top Product
    Discover our top product REEP1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Receptor Accessory Protein 1 (REEP1)
    Autre désignation
    REEP1 (REEP1 Produits)
    Synonymes
    anticorps C2orf23, anticorps HMN5B, anticorps SPG31, anticorps D6Ertd253e, anticorps RGD1305230, anticorps receptor accessory protein 1, anticorps REEP1, anticorps Reep1
    Sujet

    Synonyms: C2orf23, Chromosome 2 open reading frame 23, FLJ13110, Receptor accessory protein 1, Receptor expression-enhancing protein 1, Reep1, REEP1_HUMAN, SPG31.

    Background: Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical for receptor-ligand recognition. Mammalian GPCR odorant receptors (ORs), when heterologously expressed in cells, are poorly expressed on the cell surface. REEP1 (receptor expression-enhancing protein 1), is a 201 amino acid multi-pass mitochondrion membrane protein that belongs to the DP1 family. REEP1 interacts with odorant receptor proteins and may enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene are the third most common cause of hereditary spastic paraplegia (HSP) after spastin and atlastin gene mutations. Mutations in the REEP1 gene also cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. The REEP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana and rice, and maps to human chromosome 2p11.2.

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