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IGHMBP2 anticorps (AA 271-355) (HRP)

IGHMBP2 Reactivité: Souris WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1411040
  • Antigène Voir toutes IGHMBP2 Anticorps
    IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
    Épitope
    • 14
    • 5
    • 2
    • 2
    • 1
    AA 271-355
    Reactivité
    • 26
    • 19
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 34
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGHMBP2 est conjugé à/à la HRP
    Application
    • 21
    • 13
    • 13
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SMUBP2
    Isotype
    IgG
    Top Product
    Discover our top product IGHMBP2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    IGHMBP2 (Immunoglobulin mu Binding Protein 2 (IGHMBP2))
    Autre désignation
    SMUBP2 (IGHMBP2 Produits)
    Synonymes
    anticorps NV12364, anticorps CATF1, anticorps HCSA, anticorps HMN6, anticorps SMARD1, anticorps SMUBP2, anticorps ZFAND7, anticorps AEP, anticorps Catf1, anticorps RIPE3b1, anticorps Smbp-2, anticorps Smbp2, anticorps Smubp2, anticorps nmd, anticorps sma, anticorps RIP-1, anticorps RIP1, anticorps immunoglobulin mu binding protein 2, anticorps IGHMBP2, anticorps Ighmbp2, anticorps ighmbp2
    Sujet

    Synonyms: AEP, Antreeze enhancer binding protein, ATP-dependent helicase IGHMBP2, Cardiac transcription factor 1, Cardiac transcription factor1, CATF 1, CATF1, DNA-binding protein SMUBP-2, GF-1, Glial factor 1, HCSA, HMN 6, HMN6, IGHMBP 2, Ighmbp2, Immunoglobulin mu binding protein 2, Immunoglobulin mu binding protein2, Immunoglobulin mu-binding protein 2, Immunoglobulin S mu binding protein 2, Immunoglobulin S mu binding protein2, RIPE3 b1, RIPE3b 1, RIPE3b1, SMARD 1, SMARD1, SMBP2_HUMAN, SMUBP 2.

    Background: IGHMBP2 is a 993 amino acid nuclear and cytoplasmic protein that is ubiquitously expressed. Belonging to the DNA2/NAM7 helicase family, IGHMBP2 is a 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. IGHMBP2 also acts as a transcriptional regulator and is necessary for transcriptional activation of the flounder liver-type antifreeze protein gene. IGHMBP2 exists as a homooligomer and is part of the cytosolic ribonucleoprotein complex. Mutations in the gene encoding IGHMBP2 are suggested to lead to distal hereditary motor neuronopathy type 6 (HMN6), also known as spinal muscular atrophy distal autosomal recessive 1 (DSMA1) or spinal muscular atrophy with respiratory distress 1 (SMARD1). HMN6 is characterized by weakness and wasting of distal muscles of the anterior tibial and peroneal compartments of the legs and severe respiratory distress.

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