SPG21 anticorps (AA 151-250) (Cy7)

N° du produit ABIN1411200

Cet anticorps anti-SPG21 est un anticorps Lapin Polyclonal détectant SPG21 dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour SPG21 anticorps (AA 151-250) (Cy7) (ABIN1411200)

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG21 est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SPG21 anticorps (Cy7)

Épitope: AA 151-250

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SPG21

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SPG21

Antigène: SPG21 (Spastic Paraplegia 21 (SPG21))

Autre désignation: SPG21

Sujet:

Synonyms: Acid cluster protein 33, ACP33, BM019, BM-019, GL010, MAST, Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21 antibody, SPG21_HUMAN.

Background: Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.