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SPG21 anticorps (AA 151-250) (Cy7)

SPG21 Reactivité: Humain WB, IF (p), IF (cc) Hôte: Lapin Polyclonal Cy7
N° du produit ABIN1411200
  • Antigène Voir toutes SPG21 Anticorps
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Épitope
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 151-250
    Reactivité
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 3
    Lapin
    Clonalité
    • 24
    • 2
    Polyclonal
    Conjugué
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPG21 est conjugé à/à la Cy7
    Application
    • 19
    • 12
    • 12
    • 10
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SPG21
    Isotype
    IgG
    Top Product
    Discover our top product SPG21 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Autre désignation
    SPG21 (SPG21 Produits)
    Synonymes
    anticorps ACP33, anticorps GL010, anticorps MAST, anticorps BM-019, anticorps C78576, anticorps D9Wsu18e, anticorps Maspardin, anticorps wu:fd07h02, anticorps zgc:73091, anticorps SPG21, maspardin, anticorps spastic paraplegia 21 (autosomal recessive, Mast syndrome), anticorps SPG21, maspardin S homeolog, anticorps SPG21, anticorps Spg21, anticorps spg21.S, anticorps spg21
    Sujet

    Synonyms: Acid cluster protein 33, ACP33, BM019, BM-019, GL010, MAST, Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21 antibody, SPG21_HUMAN.

    Background: Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.

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