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ZFHX3 anticorps (AA 301-400) (Cy5)

ZFHX3 Reactivité: Rat IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1411318
  • Antigène Voir toutes ZFHX3 Anticorps
    ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
    Épitope
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivité
    • 15
    • 15
    • 10
    Rat
    Hôte
    • 26
    • 2
    • 1
    Lapin
    Clonalité
    • 28
    • 1
    Polyclonal
    Conjugué
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZFHX3 est conjugé à/à la Cy5
    Application
    • 12
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ATBF1
    Isotype
    IgG
    Top Product
    Discover our top product ZFHX3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
    Autre désignation
    ATBF1 (ZFHX3 Produits)
    Synonymes
    anticorps ZFHX3, anticorps ATBF1, anticorps ATBT, anticorps ZNF927, anticorps A230102L03Rik, anticorps Atbf1, anticorps WBP9, anticorps mKIAA4228, anticorps RGD1560268, anticorps zax-2, anticorps zinc finger homeobox 3, anticorps AT-binding transcription factor1, anticorps zfhx3, anticorps ZFHX3, anticorps ATBF1/ZFHX4b, anticorps Zfhx3
    Sujet

    Synonyms: Alpha fetoprotein enhancer binding protein, AT binding transcription factor 1, AT mot binding factor, ATBT, ZFHX3, ZFHX3_HUMAN.

    Background: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (13). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).

    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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