DLGAP1 anticorps (AA 241-360) (HRP)

N° du produit ABIN1413278

L’anticorps Lapin Polyclonal anti-DLGAP1 a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter DLGAP1 dans des échantillons de Humain.

Aperçu rapide pour DLGAP1 anticorps (AA 241-360) (HRP) (ABIN1413278)

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLGAP1 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DLGAP1 anticorps (HRP)

Épitope: AA 241-360

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SAPAP1/DLGAP1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DLGAP1

Antigène: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Autre désignation: SAPAP1/DLGAP1

Sujet:

Synonyms: PSD95 binding protein 1, DAP 1 ALPHA, DAP 1, DAP 1 BETA, DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, Discs large Drosophila homolog associated protein 1, Discs large homolog associated protein 1, Disks large associated protein 1, Disks large associated protein 1, alpha isoform, included, Disks large associated protein 1, beta isoform, included, Disks large-associated protein 1, DLGAP 1, Dlgap1, DLGP1_HUMAN, GKAP, GKAP/SAPAP, GKPA/SAPAP, Guanylate kinase associated protein, Guanylate kinase-associated protein, hGKAP, KIAA4162, MGC88156, mKIAA4162, PSD 95/SAP90 binding protein 1, PSD-95/SAP90-binding protein 1, SAP90/PSD 95 associated protein 1, SAP90/PSD-95-associated protein 1, SAPAP 1, SAPAP1.

Background: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-a, DAP-1-b, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP, through the guanylate kinase domain. GKAP is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. GKAP is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.