DLGAP4 anticorps (AA 261-370) (HRP)
Aperçu rapide pour DLGAP4 anticorps (AA 261-370) (HRP) (ABIN1413290)
Antigène
Voir toutes DLGAP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 261-370
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Réactivité croisée
- Souris, Rat
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Homologie
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SAPAP4/DLGAP4
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))
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Autre désignation
- SAPAP4/DLGAP4
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Sujet
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Synonyms: DAP 4, DAP-4, DAP4, Discs, large Drosophila homolog associated protein 4, Disks large associated protein 4, Disks large-associated protein 4, DLGAP4, DLGP4_HUMAN, DLP4, PSD 95/SAP90 binding protein 4, PSD-95/SAP90-binding protein 4, RP5-977B1.6, SAP90/PSD-95-associated protein 4, SAPAP 4, SAPAP-4, SAPAP4.
Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP4 is a 992 amino acid protein that likely localizes to the postsynaptic membrane of neurons to enhance neuronal signaling. SAPAP4 could act as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP4, DLGAP4, maps to human chromosome 20. Comprising approximately 2 % of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Antigène
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