DLGAP4 anticorps (AA 261-370) (HRP)

N° du produit ABIN1413290

L’anticorps anti-DLGAP4 Polyclonal Lapin est utilisé pour la détection de DLGAP4 dans des échantillons de Souris et Rat. Il a été validé pour WB, ELISA, IHC (p) et IHC (fro).

Aperçu rapide pour DLGAP4 anticorps (AA 261-370) (HRP) (ABIN1413290)

Antigène: DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLGAP4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DLGAP4 anticorps (HRP)

Épitope: AA 261-370

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SAPAP4/DLGAP4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DLGAP4

Antigène: DLGAP4 (Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4))

Autre désignation: SAPAP4/DLGAP4

Sujet:

Synonyms: DAP 4, DAP-4, DAP4, Discs, large Drosophila homolog associated protein 4, Disks large associated protein 4, Disks large-associated protein 4, DLGAP4, DLGP4_HUMAN, DLP4, PSD 95/SAP90 binding protein 4, PSD-95/SAP90-binding protein 4, RP5-977B1.6, SAP90/PSD-95-associated protein 4, SAPAP 4, SAPAP-4, SAPAP4.

Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP4 is a 992 amino acid protein that likely localizes to the postsynaptic membrane of neurons to enhance neuronal signaling. SAPAP4 could act as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP4, DLGAP4, maps to human chromosome 20. Comprising approximately 2 % of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.