KCNJ10 anticorps (HRP)

N° du produit ABIN1413962

L’anticorps anti-KCNJ10 Polyclonal Lapin est utilisé pour la détection de KCNJ10 dans des échantillons de Humain. Il a été validé pour IHC (fro) et IHC (p).

Aperçu rapide pour KCNJ10 anticorps (HRP) (ABIN1413962)

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ10 est conjugé à/à la HRP

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KCNJ10 anticorps (HRP)

Fonction: Kir4.1 Polyclonal Antibody, HRP Conjugated

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Kir4.1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KCNJ10

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Autre désignation: Kir4.1

Sujet:

Synonyms: ATP dependent inwardly rectying potassium channel Kir4.1, ATP sensitive inward rectier potassium channel 10, ATP-dependent inwardly rectying potassium channel Kir4.1, ATP-sensitive inward rectier potassium channel 10, BIRK10, Glial ATP dependent inwardly rectying potassium channel KIR4.1, Inward rectier K+ channel Kir1.2, Inward rectier K+ channel KIR1.2, Inwardly rectying potassium channel Kir1.2, inwardly rectying subfamily J member 10, KCNJ 10, Kcnj10, KCNJ13 PEN, KIR1.2, KIR4.1, Potassium channel, Potassium channel inwardly rectying subfamily J member 10, Potassium inwardly rectying channel subfamily J member 10, SESAME, IRK10_HUMAN.

Background: The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down?s syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.

ID gène: 3766

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity