GRM2 anticorps (Cy7)

N° du produit ABIN1414423

Cet anticorps Lapin Polyclonal détecte spécifiquement GRM2 dans IF (p). Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Chien et Poulet.

Aperçu rapide pour GRM2 anticorps (Cy7) (ABIN1414423)

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM2 est conjugé à/à la Cy7

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GRM2 anticorps (Cy7)

Réactivité croisée: Poulet, Boeuf (Vache), Chien, Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GRM2/GLUR2

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GRM2

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Autre désignation: Metabotropic Glutamate Receptor 2

Sujet:

Synonyms: Glutamate Receptor Metabotropic 2, Gprc1b, AMPA selective glutamate receptor 2, GLUR 2, GLUR2, GLURB, Glutamate receptor metabotropic 2, Metabotropic Glutamate Receptor 2, GPRC1B, GRM 2, Grm2, mGlu 2, MGlu2, MGLUR 2, Mglur2, GRM2_HUMAN.

Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Poids moléculaire: 96kDa

ID gène: 2912

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport