PANK1 anticorps (Cy3)

N° du produit ABIN1416365

L’anticorps Lapin Polyclonal anti-PANK1 a été validé pour WB et IF (p). Il convient pour détecter PANK1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PANK1 anticorps (Cy3) (ABIN1416365)

Antigène: PANK1 (Pantothenate Kinase 1 (PANK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANK1 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PANK1 anticorps (Cy3)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PANK1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PANK1

Antigène: PANK1 (Pantothenate Kinase 1 (PANK1))

Autre désignation: PANK1

Sujet:

Synonyms: coaA, hPanK, hPanK1, PANK, PANK1, PANK1_HUMAN, PANK1a, PANK1b, PanK1beta, Pantothenate kinase 1, Pantothenate kinase, Pantothenic acid kinase 1.

Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA). Pantothenate kinase 1 (PANK1) is a 598 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK1 is strongly inhibited by acetyl-CoA and manyl-CoA, as well as by high concentration of non-esterified CoA (CoASH). Four known isoforms of PANK1 exist as a result of alternative splicing events. Of these isoforms, PANK1a and PANK1b have been identified as the catalytically active isoforms. Isoform PANK1a is most highly expressed in brain, heart, kidney, liver, skeletal muscle and kidney. Isoform PANK1b is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.

ID gène: 53354

UniProt: Q8TE04

Pathways: Ribonucleoside Biosynthetic Process