FBXW4 anticorps (Cy5)

N° du produit ABIN1416678

Cet anticorps anti-FBXW4 est un anticorps Lapin Polyclonal détectant FBXW4 dans IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour FBXW4 anticorps (Cy5) (ABIN1416678)

Antigène: FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW4 est conjugé à/à la Cy5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-FBXW4 anticorps (Cy5)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SHFM3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C

Date de péremption: 12 months

Détails sur FBXW4

Antigène: FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))

Autre désignation: SHFM3

Sujet:

Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.

Synonyms: DAC, Dactylin, F box and WD 40 domain containing protein 4, F box and WD 40 domain protein 4, F box and WD repeat domain containing 4, F box/WD repeat containing protein 4, F box/WD repeat protein 4, F-box and WD-40 domain-containing protein 4, F-box/WD repeat-containing protein 4, FBW 4, FBW4, FBWD 4, FBWD4, FBXW 4, FBXW4, FBXW4_HUMAN, SHFM 3, SHSF 3, SHSF3, Split hand/foot malformation ectrodactyly type.

ID gène: 6468