GCOM1 anticorps (AA 51-150) (Cy3)

N° du produit ABIN1416749

L’anticorps Lapin Polyclonal anti-GCOM1 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter GCOM1 dans des échantillons de Souris.

Aperçu rapide pour GCOM1 anticorps (AA 51-150) (Cy3) (ABIN1416749)

Antigène: GCOM1 (GRINL1A Complex Locus (GCOM1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCOM1 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GCOM1 anticorps (Cy3)

Épitope: AA 51-150

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GCOM1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GCOM1

Antigène: GCOM1 (GRINL1A Complex Locus (GCOM1))

Autre désignation: GCOM1

Sujet:

Synonyms: Gcom2, Glutamate receptor ionotropic N methyl D aspartate like 1A combined, GRINL1A, GRINL1A combined protein, GRINL1A combined protein Gcom12, GRINL1A upstream protein, Gup1, Gup2, NMDAR1 subunit interacting protein.

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.

ID gène: 145781