FBXL5 anticorps (AA 31-130) (HRP)

N° du produit ABIN1417138

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXL5 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour FBXL5 anticorps (AA 31-130) (HRP) (ABIN1417138)

Antigène: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXL5 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-FBXL5 anticorps (HRP)

Épitope: AA 31-130

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FBXL5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FBXL5

Antigène: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Autre désignation: FBXL5

Sujet:

Synonyms: F box and leucine rich repeat protein 5, F box/LRR repeat protein 5, F-box and leucine-rich repeat protein 5, F-box protein FBL4/FBL5, F-box/LRR-repeat protein 5, FBL4, FBL5, FBXL5, FBXL5_HUMAN, FLR1, p45SKP2 like protein, p45SKP2-like protein.

Background: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

ID gène: 26234

Pathways: Transition Metal Ion Homeostasis