FBXO36 anticorps (AA 1-100) (Cy7)

N° du produit ABIN1417148

L’anticorps Lapin Polyclonal anti-FBXO36 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter FBXO36 dans des échantillons de Souris.

Aperçu rapide pour FBXO36 anticorps (AA 1-100) (Cy7) (ABIN1417148)

Antigène: FBXO36 (F-Box Protein 36 (FBXO36))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO36 est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-FBXO36 anticorps (Cy7)

Épitope: AA 1-100

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FBXO6

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FBXO36

Antigène: FBXO36 (F-Box Protein 36 (FBXO36))

Autre désignation: FBXO36

Sujet:

Synonyms: F box only protein 36, F box protein 36, F-box only protein 36, Fbx 36, Fbx36, FBX36_HUMAN, FBXO 36, Fbxo36, FLJ37592, FLJ41090.

Background: FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and -catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation.

ID gène: 130888

UniProt: Q8NEA4