TENM3 anticorps (HRP)

N° du produit ABIN1418482

Cet anticorps Lapin Polyclonal détecte spécifiquement TENM3 dans IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TENM3 anticorps (HRP) (ABIN1418482)

Antigène: TENM3 (ODZ3) (Teneurin 3 (ODZ3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TENM3 est conjugé à/à la HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TENM3 anticorps (HRP)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ODZ3/Teneurin 3

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TENM3

Antigène: TENM3 (ODZ3) (Teneurin 3 (ODZ3))

Autre désignation: ODZ3

Sujet:

Synonyms: ODZ3 like protein, Protein Odd Oz ten m homolog 3, Ten 3, Ten M3, Tenascin M3, Teneurin 3, Teneurin3, TNM3, FLJ10474, FLJ10886, KIAA1455, odd Oz Ten m homolog 3, odz odd Oz ten m homolog 3 Drosophila, odz odd Oz ten m homolog 3, TEN3_HUMAN.

Background: Teneurin-3, also known as Ten-3, TNM3 or ODZ3, is a 2,699 amino acid single-pass type II membrane protein that contains 25 YD repeats, 8 EGF-like domains, 5 NHL repeats and one teneurin N-terminal domain. Localized to the membrane and expressed in brain, testis and ovary, Teneurin-3 exists as a disulfide-liked homodimer that is thought to function as a cellular signal transducer. Additionally, Teneurin-3 may participate in eye-specific patterning in the visual pathway and is required for aligned binocular vision. The gene encoding Teneurin-3 maps to chromosome 4. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.