HDGFRP2 anticorps (Cy3)

N° du produit ABIN1418543

L’anticorps Lapin Polyclonal anti-HDGFRP2 a été validé pour WB et IF (p). Il convient pour détecter HDGFRP2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HDGFRP2 anticorps (Cy3) (ABIN1418543)

Antigène: HDGFRP2 (Hepatoma-Derived Growth Factor-Related Protein 2 (HDGFRP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDGFRP2 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-HDGFRP2 anticorps (Cy3)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HRP2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HDGFRP2

Antigène: HDGFRP2 (Hepatoma-Derived Growth Factor-Related Protein 2 (HDGFRP2))

Autre désignation: HRP2

Sujet:

Synonyms: HDGF-2, Hdgfrp2, HDGR2_HUMAN, Hepatoma-derived growth factor 2, Hepatoma-derived growth factor, Hepatoma-derived growth factor-related protein 2, heptoma derived growth factor related protein 2, HRP-2.

Background: Hepatoma Derived Growth Factor (HDGF) is the original member of a family of polypeptides designated HDGF-related proteins (HRPs). HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. This nuclear targeted vascular smooth muscle cell mitogen (VSM) is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. During development, HDGF expression is high in the nucleus and cytoplasm of smooth muscle and endothelial cells. The HRP (HDGF related proteins) family contains four proteins, HRP-1, HRP-2, HRP-3 and HRP-4. HRP-1 and HRP-4 are only expressed in testis while HRP-2 is widely expressed in different tissues. HRP-3 can solely be found in the nervous system. Specifically it is strongly expressed in bulbus, olfactorius, piriform cotrex and amygdala complex while HRP-2 in brain is located in the the thalamus, prefrontal and parietal cortex, neurohypophysis, and the cerebellum. In the central nervous system, HRP proteins are play a role in neuron proliferation and cell survival.