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MARCH9 anticorps (Cy5)

MARCH9 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1420044
  • Antigène Voir toutes MARCH9 Anticorps
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    Reactivité
    • 41
    • 24
    • 21
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 38
    • 2
    Lapin
    Clonalité
    • 39
    • 2
    Polyclonal
    Conjugué
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MARCH9 est conjugé à/à la Cy5
    Application
    • 40
    • 16
    • 12
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MARCH9
    Isotype
    IgG
    Top Product
    Discover our top product MARCH9 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    Autre désignation
    MARCH9 (MARCH9 Produits)
    Synonymes
    anticorps Rnf179, anticorps March-IX, anticorps MARCH-IX, anticorps RNF179, anticorps AI608492, anticorps BC019560, anticorps membrane associated ring-CH-type finger 9, anticorps membrane associated ring-CH-type finger 9 S homeolog, anticorps membrane-associated ring finger (C3HC4) 9, anticorps March9, anticorps march9.S, anticorps MARCH9, anticorps march9
    Sujet

    Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.

    ID gène
    92979
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