ANGEL2 anticorps (HRP)

N° du produit ABIN1422274

Cet anticorps Lapin Polyclonal détecte spécifiquement ANGEL2 dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ANGEL2 anticorps (HRP) (ABIN1422274)

Antigène: ANGEL2 (Angel Homolog 2 (ANGEL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANGEL2 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ANGEL2 anticorps (HRP)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ANGEL2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ANGEL2

Antigène: ANGEL2 (Angel Homolog 2 (ANGEL2))

Autre désignation: ANGEL2

Sujet:

Synonyms: NGE2_HUMAN, Angel homolog 2, angel2, Protein angel homolog 2.

Background: ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3_5_-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.

ID gène: 90806