SLURP1 anticorps (Cy7)
Aperçu rapide pour SLURP1 anticorps (Cy7) (ABIN1423304)
Antigène
Voir toutes SLURP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SLURP1/ANUP
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Isotype
- IgG
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Indications d'application
- IF(IHC-P) 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- SLURP1 (Secreted LY6/PLAUR Domain Containing 1 (SLURP1))
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Autre désignation
- ANUP
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Sujet
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Synonyms: Anti neoplastic urinary protein, ANUP, ARS, ARS component B, ARScomponent B 81/S, ArsB, LY6LS, Lymphocyte antigen 6 like secreted, MDM, Results in cobblestone changes in the skin of the palm, Secreted Ly 6/uPAR related protein 1, Secreted LY6/PLAUR domain containing 1, Secreted Ly6/uPAR related protein 1, SLURP-1, SLURP1, SLUR1_HUMAN.
Background: SLURP1, also known as MDM, ARS, ANUP (anti-neoplastic urinary protein), LY6LS or ArsB (ARS component B), is a 103 amino acid secreted protein that exists as a homodimer possessing antitumor activity. Found in esophagus, stomach, exocervix, gums, urine, sweat, saliva, plasma and tears, SLURP1 is most highly expressed in the acrosyringium of the granular layer of skin, where it helps maintain the structure of the keratinocyte layers of the skin. Also considered a marker for late skin differentiation, SLURP1 contains one UPAR/Ly6 domain and is the cause of an autosomal recessive disorder of the skin known as Mal de Meleda (MDM). MDM Is characterized by nail abnormalities, keratotic skin lesions, transgressive palmoplantar keratoderma (PPK), perioral erythema and may sometimes include hyperhidrosis.
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ID gène
- 57152
Antigène
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