SLURP1 anticorps (HRP)

N° du produit ABIN1423306

Cet anticorps Lapin Polyclonal détecte spécifiquement SLURP1 dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour SLURP1 anticorps (HRP) (ABIN1423306)

Antigène: SLURP1 (Secreted LY6/PLAUR Domain Containing 1 (SLURP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLURP1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SLURP1 anticorps (HRP)

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLURP1/ANUP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SLURP1

Antigène: SLURP1 (Secreted LY6/PLAUR Domain Containing 1 (SLURP1))

Autre désignation: ANUP

Sujet:

Synonyms: Anti neoplastic urinary protein, ANUP, ARS, ARS component B, ARScomponent B 81/S, ArsB, LY6LS, Lymphocyte antigen 6 like secreted, MDM, Results in cobblestone changes in the skin of the palm, Secreted Ly 6/uPAR related protein 1, Secreted LY6/PLAUR domain containing 1, Secreted Ly6/uPAR related protein 1, SLURP-1, SLURP1, SLUR1_HUMAN.

Background: SLURP1, also known as MDM, ARS, ANUP (anti-neoplastic urinary protein), LY6LS or ArsB (ARS component B), is a 103 amino acid secreted protein that exists as a homodimer possessing antitumor activity. Found in esophagus, stomach, exocervix, gums, urine, sweat, saliva, plasma and tears, SLURP1 is most highly expressed in the acrosyringium of the granular layer of skin, where it helps maintain the structure of the keratinocyte layers of the skin. Also considered a marker for late skin differentiation, SLURP1 contains one UPAR/Ly6 domain and is the cause of an autosomal recessive disorder of the skin known as Mal de Meleda (MDM). MDM Is characterized by nail abnormalities, keratotic skin lesions, transgressive palmoplantar keratoderma (PPK), perioral erythema and may sometimes include hyperhidrosis.

ID gène: 57152