CD276 anticorps (AA 120-170) (PE)

N° du produit ABIN1424420

L’anticorps Lapin Polyclonal anti-CD276 a été validé pour WB. Il convient pour détecter CD276 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CD276 anticorps (AA 120-170) (PE) (ABIN1424420)

Antigène: CD276

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD276 est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-CD276 anticorps (PE)

Épitope: AA 120-170

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CD276/B7H3

Isotype: IgG

Information d'application

Indications d'application: FCM(1:20-100)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CD276

Antigène: CD276

Autre désignation: Cd276/B7h3

Sujet:

Synonyms: B7H3, B7-H3, B7RP-2, 4Ig-B7-H3, CD276 antigen, B7 homolog 3, Costimulatory molecule, CD276, PSEC0249, UNQ309/PRO352

Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

ID gène: 80381

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints