DSCAM anticorps (PE)

N° du produit ABIN1426575

Cet anticorps anti-DSCAM est un anticorps Lapin Polyclonal détectant DSCAM dans FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour DSCAM anticorps (PE) (ABIN1426575)

Antigène: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DSCAM est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-DSCAM anticorps (PE)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Dscam

Isotype: IgG

Information d'application

Indications d'application: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4 °C

Date de péremption: 12 months

Détails sur DSCAM

Antigène: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Autre désignation: Dscam

Sujet:

DSCAM is a cell adhesion molecule belonging to the immunoglobulin superfamily. It is predominantly expressed in brain and contains six Fibronectin type-III domains and ten Ig-like C2-type domains. In mice, DSCAM is responsible for regulating isoneuronal self-avoidance, the tendency for sister arbors to avoid crossing each other and to spread out proportionately over an area. Isoneuronal self-avoidance is important for proper terminal branching (arborization). In some cell types, DSCAM also mediates heteroneuronal self-avoidance, which is important for the regular spacing of cell bodies and the prevention of hyperfasciculation. In humans, two DSCAM isoforms exist due to alternative splicing. The long isoform (also known as CHD2-42) is a single pass type I membrane protein, while the short isoform (CHD2-52), which lacks the C-terminal transmembrane containing region (amino acids 1572-2012), is secreted.

Subcellular location: Extracellular

Synonyms: CHD2 42, CHD2 52, CHD2, Down syndrome cell adhesion molecule, DSCAM, DSCAM_HUMAN, human CHD2-52 down syndrome cell adhesion molecule 2, 9, OTTHUMP00000109193 2, SD11109p.

Pathways: Regulation of Cell Size