KIRREL3 anticorps (PE-Cy5)
Aperçu rapide pour KIRREL3 anticorps (PE-Cy5) (ABIN1428572)
Antigène
Voir toutes KIRREL3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Réactivité croisée
- Souris
-
Homologie
- Human,Rat,Chicken
-
Purification
- Purified by Protein A.
-
Immunogène
- KLH conjugated synthetic peptide derived from human KIRREL3
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Date de péremption
- 12 months
-
-
- KIRREL3 (Kin of IRRE Like 3 (KIRREL3))
-
Autre désignation
- KIRREL3
-
Sujet
-
Synonyms: Kin of IRRE like 3 Drosophila, Kin of IRRE like 3, Kin of irregular chiasm like protein 3 , KIRRE, KIRREL 3, KIRREL-3, MRD4, NEPH2, Nephrin like 2, PRO19814, PRO4502, yUNQ5923, KIRR3_HUMAN.
Background: NEPH2 is a 778 amino acid single-pass type I membrane protein that belongs to the nephrin-like protein family and immunoglobulin superfamily. Expressed in both fetal and adult brain, as well as podocytes of kidney glomeruli, NEPH2 contains five Ig-like C2-type (immunoglobulin-like) domains and is thought to plaly a role in the hematopoetic supportive capacity of stroma cells. NEPH2 undergoes alternative splicing to produce two isoforms and contains a C-terminal cytoplasmic domain which it uses to interact with Podocin, a podocyte protein involved in ultrafiltration. Defects in the gene encoding NEPH2 are associated with mental retardation autosomal dominant type 4 (MRD4).
-
Poids moléculaire
- 83kDa
Antigène
-