GABRA6 anticorps (PE-Cy7)

N° du produit ABIN1429544

L’anticorps Lapin Polyclonal anti-GABRA6 a été validé pour WB. Il convient pour détecter GABRA6 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour GABRA6 anticorps (PE-Cy7) (ABIN1429544)

Antigène: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABRA6 est conjugé à/à la PE-Cy7

Application: Western Blotting (WB)

Détail du produit anti-GABRA6 anticorps (PE-Cy7)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GABRA6

Antigène: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Autre désignation: GABRA6/GABA A Receptor alpha 6

Sujet:

Synonyms: GABA A, GABA A Receptor alpha 6 polypeptide, GABA A receptor alpha 6, GABA A receptor subunit alpha 6, GABA subunit A receptor alpha 6, GABAA receptor subunit alpha-6, GABRA 6, GABRA6, Gamma aminobutyric acid A receptor alpha 6, Gamma aminobutyric acid GABA A receptor alpha 6, Gamma aminobutyric acid receptor subunit alpha 6, Gamma-aminobutyric acid receptor subunit alpha-6, GBRA6_HUMAN, MGC116903, MGC116904.

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R gamma 1-3, GABAA R gamma , GABAA R delta. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Poids moléculaire: 49kDa

ID gène: 2559

UniProt: Q16445

Pathways: Synaptic Membrane