KCNT2 anticorps (PE)

N° du produit ABIN1430095

Cet anticorps Lapin Polyclonal détecte spécifiquement KCNT2 dans FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour KCNT2 anticorps (PE) (ABIN1430095)

Antigène: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNT2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-KCNT2 anticorps (PE)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KCNT2

Isotype: IgG

Information d'application

Indications d'application: FCM(1:20-100)

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C

Date de péremption: 12 months

Détails sur KCNT2

Antigène: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Autre désignation: Kcnt2

Sujet:

Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.

Subcellular location: Extracellular

Synonyms: KCa4.2, Potassium channel, subfamily T, member 2, Sequence like an intermediate conductance potassium channel subunit, SLICK, SLO2.1, Sodium and chloride activated ATP sensitive potassium channel, Sodium and chloride activated ATP sensitive potassium channel Slo2.1, KCNT2_HUMAN.