ZNRF1 anticorps (PE)

N° du produit ABIN1434627

Cet anticorps anti-ZNRF1 est un anticorps Lapin Polyclonal détectant ZNRF1 dans IF (p). Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien et Poulet.

Aperçu rapide pour ZNRF1 anticorps (PE) (ABIN1434627)

Antigène: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNRF1 est conjugé à/à la PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ZNRF1 anticorps (PE)

Réactivité croisée: Rat (Rattus), Poulet, Chien, Boeuf (Vache)

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic peptide derived from human ZNRF1

Isotype: IgG

Information d'application

Commentaires:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur ZNRF1

Antigène: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Autre désignation: ZNRF1

Sujet: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. ZNRF1 (zinc and ring finger 1), also known as NIN283, is a 227 amino acid protein that contains one RING-type zinc finger and localizes to the lysosome and the endosome, as well as to cytoplasmic vesicles and the peripheral membrane. Expressed primarily in nervous system tissue, but also present in testis and thymus, ZNRF1 functions as an E3 ubiquitin-protein ligase that is thought to play a role in the establishment and maintenance of neuronal plasticity. Multiple isoforms of ZNRF1 exist due to alternative splicing events.

ID gène: 84937

HGNC: 0