ARL6IP5 anticorps (PE)

N° du produit ABIN1437247

Cet anticorps Lapin Polyclonal détecte spécifiquement ARL6IP5 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ARL6IP5 anticorps (PE) (ABIN1437247)

Antigène: ARL6IP5 (Arl6ip5) (ADP-Ribosylation-Like Factor 6 Interacting Protein 5 (Arl6ip5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL6IP5 est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-ARL6IP5 anticorps (PE)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human JWA

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ARL6IP5

Antigène: ARL6IP5 (Arl6ip5) (ADP-Ribosylation-Like Factor 6 Interacting Protein 5 (Arl6ip5))

Autre désignation: JWA

Sujet:

Synonyms: Addicsin, ADP ribosylation like factor 6 interacting protein 5, Aip 5, Aip5, ARL 6 interacting protein 5, ARL6IP5 antibody Cytoskeleton related vitamin A responsive protein, Dermal papilla derived protein 11, DERP 11, DERP11, Glutamate transporter EEAC 1 associated protein, Glutamate transporter EEAC1 associated protein, GTRAP3 18, Hp 22, Hp22, HSPC 127, HSPC127, JM 5, JM5, JMX, PRA 1 domain family 3, PRA 2, PRA1 domain family 3, PRA2, PRAF 3, PRAF3, Prenylated Rab acceptor protein 2, Protein JWa, Putative MAPK activating protein PM27, PRAF3_HUMAN.

Background: JWA is a four-transmembrane environmental responsive protein which binds to the CC chemokine recepor 5 (CCR5), a major co-receptor for human immunodeficiency virus (HIV). JWA is involved in environmental stress-responsive pathways in K562 cells, an erythroleukemia cell line derived from patients with chronic myeloid leukemia. Environmental stressors to K562 cells such as heat shock, a higher temperature than the ideal body temperature of the organism from which the cell line was derived, and oxidative stress, the production of oxygen-centered free radicals, regulate and increase the expres-sion of JWA. This response to environmental stressors suggests similiarity of JWA to heat shock protein 70 (HSP70), which is upregulated by heat stress and toxic chemicals.

ID gène: 10550

Pathways: Dicarboxylic Acid Transport