ATP1A1 anticorps

N° du produit ABIN1449189

Cet anticorps anti-ATP1A1 Monoclonal Souris (Clone 9A7) (ABIN1449189) détecte spécifiquement ATP1A1 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour ATP1A1 anticorps (ABIN1449189)

Antigène: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATP1A1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 9A7

Détail du produit anti-ATP1A1 anticorps

Specificité: This antibody reacts with human Na+/K+ ATPase α subunit.

Purification: Protein A agarose

Immunogène: Chicken brain synaptic membrane

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur ATP1A1

Antigène: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Autre désignation: ATP1A1

Sujet: Na+/K+-ATPase is an integral membrane protein complex that is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. Na+/K+-ATPase hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+. The Na+/K+-ATPase consists of a large transmembrane catalytic subunit, termed the a subunit, and an associated smaller glycoprotein, termed the ß subunit, that appears to be necessary for the assembly and transport of the sodium pump to the plasma membrane. There are three isoforms of the a subunit (a-1, -2, and -3) and two isoforms of the ß subunit (ß-1 and -2) encoded by two multigene families. The a-1 and ß mRNAs are present in all cell types examined, whereas the a-2 and a-3 mRNAs exhibit a more restricted pattern of cell-specific expression. The a subunit protein has been found in kidney, brain (both neuronal and non-neuronal cells), heart, and to a lesser extent liver, skeletal and smooth muscle.Synonyms: Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1

Poids moléculaire: 80 kDa

ID gène: 476

NCBI Accession: NP_000692

UniProt: P05023

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process