RAN anticorps
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- Antigène Voir toutes RAN Anticorps
- RAN (RAN, Member RAS Oncogene Family (RAN))
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Reactivité
- Humain, Souris, Rat, Hamster
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp RAN est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Specificité
- This antibody reacts with Ran. ARAN1 inhibits the basic type NLS-dependent nuclear protein import. ARAN1 recognizes an epitope located the residues between 207 and 216 of human Ran.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat, Hamster
- Purification
- Protein A agarose
- Immunogène
- Recombinant human Ran
- Clone
- ARAN1
- Isotype
- IgG2b
- Top Product
- Discover our top product RAN Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Upon receipt, store (in aliqouts) at -20 °C.
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- Antigène
- RAN (RAN, Member RAS Oncogene Family (RAN))
- Autre désignation
- RAN (RAN Produits)
- Synonymes
- anticorps ARA24, anticorps Gsp1, anticorps TC4, anticorps ran, anticorps ara24, anticorps gsp1, anticorps ran-1, anticorps tc4, anticorps RAN, anticorps RANP1, anticorps AAF30287, anticorps CG1404, anticorps Dmel\CG1404, anticorps Ran, anticorps dran, anticorps l(1)G0075, anticorps ran10A, anticorps fc16b04, anticorps wu:fc16b04, anticorps RAN, member RAS oncogene family, anticorps RAN, member RAS oncogene family S homeolog, anticorps CG1404 gene product from transcript CG1404-RC, anticorps RAN, anticorps Ran, anticorps ran.S, anticorps ran
- Sujet
- The Ran GTPase has important roles in nucleocytoplasmic transport, cell cycle progression, nuclear organization and nuclear envelope (NE) assembly. The small GTPase Ran is essential for spindle assembly. Ran is proposed to act through its nuclear import receptors importin and/or importin to control the sequestration of proteins necessary for spindle assembly. Ran, is required for coordinating the onset of mitosis with S-phase completion in mammalian cells. Other defects in the Ran-GTPase network also result in disruption of cell-cycle processes such as DNA replication, exit from mitosis and, at least in budding yeast, accurate chromosome segregation.Synonyms: ARA24, Androgen receptor-associated protein 24, GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein
- Poids moléculaire
- 25 kDa
- ID gène
- 5901
- NCBI Accession
- NP_006316
- UniProt
- P62826
- Pathways
- Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
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