KPNB1 anticorps

N° du produit ABIN1449199

Cet anticorps Rat Monoclonal détecte spécifiquement KPNB1 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour KPNB1 anticorps (ABIN1449199)

Antigène: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Reactivité: Humain, Souris, Rat

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp KPNB1 est non-conjugé

Application: Western Blotting (WB)

Clone: 1D7

Détail du produit anti-KPNB1 anticorps

Specificité: This antibody detects Importin β.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein G agarose

Immunogène: Recombinant full-length mouse importin beta

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur KPNB1

Antigène: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Autre désignation: NTF97

Sujet: Importin ß (karyopherin ß/PTAC97) forms a complex with importin a that is required for classical import of proteins across the nuclear envelope through the nuclear pore complex. Importin a acts as a bridge between the nuclear localization sequence (NLS) and importin ß, while importin ß is the site of initial docking to the pore and is responsible for transport of the target protein into the nucleus. Inside the nucleus, Ran-GTP binds to importin ß, resulting in dissociation of the ternary complex, and importin a and ß are independently recycled back into the cytoplasm. Recently some NLS-containing proteins have been shown to bind directly to importin ß and enter the nucleus in an importin a independent manner.Synonyms: Importin subunit beta-1, Importin-90, KPNB1, Nuclear factor P97

Poids moléculaire: 96 kDa

ID gène: 3837

NCBI Accession: NP_002256

UniProt: Q14974

Pathways: Protein targeting to Nucleus