KPNB1 anticorps
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- Antigène Voir toutes KPNB1 Anticorps
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KPNB1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects Importin β.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Protein G agarose
- Immunogène
- Recombinant full-length mouse importin beta
- Clone
- 1D7
- Isotype
- IgG2a
- Top Product
- Discover our top product KPNB1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Upon receipt, store (in aliqouts) at -20 °C.
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- Antigène
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
- Autre désignation
- NTF97 (KPNB1 Produits)
- Synonymes
- anticorps Afu1g15720, anticorps AO090005001133, anticorps imb1, anticorps impnb, anticorps ipo1, anticorps ipob, anticorps ntf97, anticorps IMB1, anticorps IPO1, anticorps IPOB, anticorps Impnb, anticorps NTF97, anticorps AA409963, anticorps importin beta-1 subunit, anticorps Importin beta-1 subunit, anticorps karyopherin (importin) beta 1 L homeolog, anticorps importin beta 1, anticorps karyopherin subunit beta 1, anticorps karyopherin (importin) beta 1, anticorps AFUA_1G15720, anticorps AOR_1_1974174, anticorps Bm1_57540, anticorps PMAA_065830, anticorps AFLA_083750, anticorps TSTA_085870, anticorps BDBG_07509, anticorps MCYG_00039, anticorps kpnb1.L, anticorps LOC100533387, anticorps KPNB1, anticorps Kpnb1
- Sujet
- Importin ß (karyopherin ß/PTAC97) forms a complex with importin a that is required for classical import of proteins across the nuclear envelope through the nuclear pore complex. Importin a acts as a bridge between the nuclear localization sequence (NLS) and importin ß, while importin ß is the site of initial docking to the pore and is responsible for transport of the target protein into the nucleus. Inside the nucleus, Ran-GTP binds to importin ß, resulting in dissociation of the ternary complex, and importin a and ß are independently recycled back into the cytoplasm. Recently some NLS-containing proteins have been shown to bind directly to importin ß and enter the nucleus in an importin a independent manner.Synonyms: Importin subunit beta-1, Importin-90, KPNB1, Nuclear factor P97
- Poids moléculaire
- 96 kDa
- ID gène
- 3837
- NCBI Accession
- NP_002256
- UniProt
- Q14974
- Pathways
- Protein targeting to Nucleus
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