Podoplanin anticorps
Aperçu rapide pour Podoplanin anticorps (ABIN1449217)
Antigène
Voir toutes Podoplanin (PDPN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts with mouse Aggrus (Podoplanin). The reference 6) described that this antibody does not react to human Aggrus (Podoplanin).
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Purification
- Protein G agarose
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Immunogène
- NL-17 cell membrane fraction
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Upon receipt, store (in aliqouts) at -20 °C.
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- Podoplanin (PDPN)
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Autre désignation
- Podoplanin
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Sujet
- In addition to hemostasis and host defense, platelets are involved in the induction of inflammation, tissue repair, and tumor metastasis. Aggrus (T1a/Podoplanin) is a novel 36-45 kDa membrane sialoglycoprotein that induces platelet aggregation. Aggrus is highly expressed in various tumor cells and the platelet aggregation ability of Aggrus depends on specific oligosaccharide structures that may be related to the metastasis process in cancer cells. Aggrus has been identified as a diagnostic tumor marker for seminomas and testicular cancers.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha
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Poids moléculaire
- 44 kDa
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ID gène
- 10630
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NCBI Accession
- NP_001006625
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UniProt
- Q86YL7
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Pathways
- Dicarboxylic Acid Transport
Antigène
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