CD52 anticorps

N° du produit ABIN1449230

L’anticorps Rat Monoclonal anti-CD52 a été validé pour FACS et IP. Il convient pour détecter CD52 dans des échantillons de Souris.

Aperçu rapide pour CD52 anticorps (ABIN1449230)

Antigène: CD52

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD52 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: BTG-2G

Détail du produit anti-CD52 anticorps

Specificité: This antibody reacts with mouse CAMPATH-1/CD52.

Purification: Protein G agarose

Immunogène: Mouse IL-2R alpha-TGM splenocyte

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur CD52

Antigène: CD52

Autre désignation: CD52 / CAMPATH-1

Sujet: CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

ID gène: 23833

NCBI Accession: NP_038734

UniProt: Q64389