Histone H4 anticorps

N° du produit ABIN1449238

Cet anticorps Souris Monoclonal détecte spécifiquement Histone H4 dans WB, IF et IP. Il présente une réactivité envers Humain, Souris, Rat et Hamster.

Aperçu rapide pour Histone H4 anticorps (ABIN1449238)

Antigène: Histone H4

Reactivité: Humain, Souris, Rat, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: C14691

Détail du produit anti-Histone H4 anticorps

Specificité: This antibody reacts with Histone H4.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat, Hamster

Purification: Protein A agarose

Immunogène: Protein fraction extracted from the mitotic chromosome

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur Histone H4

Antigène: Histone H4

Sujet: The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-transcriptional modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H4 plays a primary role in the structural changes that mediate enhanced binding of transcription factors to their recognition sites within nucleosomes. It has been suggested that acetylated Histone H4 also is involved in heightened activation of the transcription of male X chromosomes, and that Histone H4 stimulates glucose transport activity in rat skeletal muscle.Synonyms: H4/A, H4FA, HIST1H4

Poids moléculaire: 11 kDa

ID gène: 121504

NCBI Accession: NP_001029249

UniProt: P62805