14-3-3 gamma anticorps (N-Term)

N° du produit ABIN1449274

Cet anticorps Souris Monoclonal détecte spécifiquement 14-3-3 gamma dans WB et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour 14-3-3 gamma anticorps (N-Term) (ABIN1449274)

Antigène: 14-3-3 gamma (YWHAG1)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp 14-3-3 gamma est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: KC21

Détail du produit anti-14-3-3 gamma anticorps

Épitope: AA 1-12, N-Term

Specificité: This antibody reacts with 14-3-3γ, which the N-terminal Met is removed as a result of acetylated the N-terminal Val, on Western blotting. This antibody does not recognize unprocessed (non-modified) 14-3-3γ.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Protein A agarose

Immunogène: KLH-conjugated human 14-3-3gamma N-terminal peptides (1-12 aa)

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur 14-3-3 gamma

Antigène: 14-3-3 gamma (YWHAG1)

Autre désignation: 14-3-3 Protein gamma

Sujet: The 14-3-3 protein family comprises critical regulatory molecules involved in signaling during cell division, proliferation, and apoptosis. 14-3-3 γ, a subtype of the 14-3-3 family of proteins, was thought to be brain- and neuron-specific. However, 14-3-3 γ was not neuron-specific but also expressed in astrocytes. Endogenous 14-3-3 γ proteins in immature astrocytes appeared filamentous and co-localized with filamentous actin (F-actin). And, 14-3-3 γ proteins play a role in cytoskeletal function during the process of cell division and apoptosis in astrocytes in association with actin. This expression is induced in arterial trauma by cytokines, and suggests that this protein may play an important role in progression of vascular proliferative diseases.Synonyms: KCIP-1, Protein kinase C inhibitor protein 1, YWHAG

Poids moléculaire: 33 kDa

ID gène: 7532

NCBI Accession: NP_036611

UniProt: P61981

Pathways: Myometrial Relaxation and Contraction, M Phase