ATG12 anticorps (N-Term)

N° du produit ABIN1449610

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG12 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour ATG12 anticorps (N-Term) (ABIN1449610)

Antigène: ATG12 (Autophagy Related 12 (ATG12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ATG12 anticorps

Épitope: AA 44-73, N-Term

Specificité: This antibody recognizes Human APG12L (N-term). Other species not tested.

Purification: Saturated Ammonium Sulfate precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide between 44~73 amino acids from the N-term of Human APG12L Genename: ATG12

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ATG12

Antigène: ATG12 (Autophagy Related 12 (ATG12))

Autre désignation: ATG12 / APG12

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG12L is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.Synonyms: APG12-like, APG12L, Autophagy-related protein 12, Ubiquitin-like protein ATG12

Poids moléculaire: 15113 Da

ID gène: 9140

NCBI Accession: NP_004698

Pathways: Autophagy