UVRAG anticorps (C-Term)
Aperçu rapide pour UVRAG anticorps (C-Term) (ABIN1449617)
Antigène
Voir toutes UVRAG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 670-699, C-Term
-
Purification
- Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
-
Immunogène
- KLH conjugated synthetic peptide between 670~699 amino acids from the C-term of Human UVRAG
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
-
Autre désignation
- UVRAG
-
Sujet
- UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.Synonyms: UV radiation resistance-associated gene protein, p63
-
Poids moléculaire
- 78151 Da
-
ID gène
- 7405
-
NCBI Accession
- NP_003360
Antigène
-