AFF2 anticorps (Middle Region)

N° du produit ABIN1449867

Détail du produit anti-AFF2 anticorps

Antigène: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFF2 est non-conjugé

Application: Western Blotting (WB)

Séquence: AMGNCNNGPV TIPQRIHHMA ASHVNITSNV LRGYEHWDMA DKLTRENKEF

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Horse, Rabbit, Guinea PigSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: Synthetic peptide directed towards the middle region of human AFF2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur AFF2

Antigène: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Autre désignation: AFF2 / FMR2 (AFF2 Produits)

Synonymes: anticorps FMR2, anticorps FMR2P, anticorps FRAXE, anticorps MRX2, anticorps OX19, anticorps Fmr2, anticorps Ox19, anticorps Oxh, anticorps AF4/FMR2 family member 2, anticorps AF4/FMR2 family, member 2, anticorps AFF2, anticorps Aff2

Sujet: AFF2 is a RNA-binding protein and might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. Defects in AFF2 are the cause of mental retardation X-linked associated with fragile site FRAXE (MRFRAXE). A form of mild to moderate mental retardation associated with learning difficulties, communication deficits, attention problems, hyperactivity, and autistic behavior. It is associated with a fragile site on chromosome Xq28.Synonyms: AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, Protein Ox19

ID gène: 2334

NCBI Accession: NP_002016